Sarah Mundt
Department of Neurology, University Hospital Zurich
Links
Research snapshot
Citations (1595, h 19, i10 25)
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Journals
Med (1)
Cell (1)
ALTEX (1)
Nature (1)
Neuron (1)
Immunity (1)
Autophagy (1)
Nature Aging (2)
Science advances (1)
Science Immunology (3)
Scientific reports (1)
Nature Neuroscience (3)
Blood Cancer Journal (1)
Molecular immunology (1)
Trends in Immunology (1)
Acta Neuropathologica (1)
Cell Reports Medicine (1)
EMBO molecular medicine (1)
Trends in Neurosciences (1)
European journal of immunology (2)
Clinical and experimental rheumatology (1)
Journal of Allergy and Clinical Immunology (1)
Journal of immunology (Baltimore, Md. : 1950) (1)
Neurology - Neuroimmunology Neuroinflammation (1)
Proceedings of the National Academy of Sciences of the United States of America (1)
Funding (8)
Protective Role of IL-12 in Tissue Inflammation
Forschungskredit - University of Zurich
Uncoupling inflammatory demyelination from neurodegeneration in MS
Dr. Wilhelm Hurka foundation
Neurodegeneration in progressive MS: what is the contribution of local phagocytes?
Swiss MS Society · 2020
Unravelling CNS-specific tolerance mechanisms in health and disease
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung · 2020
CNS associated T cells: Studying their fate in tissue homeostasis versus autoimmunity
FAN (Fonds zur Förderung des akademischen Nachwuchses) · 2023
Disentangling pathogenic and protective features of CNS phagocytes – a dual role of MerTK in neuroinflammation?
Swiss MS Society · 2024
Spatiotemporal characterization of progression associated monocyte derived cells (paMdCs) in mouse and human neuroinflammation
Novartis Foundation · 2024
Profiling progression associated phagocytes in CNS autoimmunity
Hartmann Müller Foundation · 2024
Papers (34)
GM-CSF derived from alveolar type 2 cells promotes CD301b⁺ cDC2 generation and allergic airway inflammation
Science Immunology · 2025
Interleukin-34-dependent perivascular macrophages promote vascular function in the brain
Immunity · 2025
PDL1-expressing macrophages infiltrate diffuse large B-cell lymphoma and promote lymphoma growth in a MYC-driven experimental model
Blood Cancer Journal · 2025
Interleukin-12 signaling drives Alzheimer’s disease pathology through disrupting neuronal and oligodendrocyte homeostasis
Nature Aging · 2025
Multimodal transcriptomics reveal neurogenic aging trajectories and age-related regional inflammation in the dentate gyrus
Nature Neuroscience · 2025
Mononuclear phagocytes in autoimmune neuroinflammation
Trends in Immunology · 2024
Regulatory T cells control type 1-driven immunopathology restraining GM-CSF-producing helper T cells
· 2024
B cell depletion attenuates CD27 signaling of T helper cells in multiple sclerosis
Cell Reports Medicine · 2024
IL-12 sensing in neurons induces neuroprotective CNS tissue adaptation and attenuates neuroinflammation in mice
Nature Neuroscience · 2023
Antibodies Produced by CLL Phenotype B Cells in Patients With Myasthenia Gravis Are Not Directed Against Neuromuscular Endplates
Neurology - Neuroimmunology Neuroinflammation · 2023
Neuroprotective tissue adaptation induced by IL-12 attenuates CNS inflammation
Nature Neuroscience · 2022
Azathioprine therapy induces selective NK cell depletion and IFN-γ deficiency predisposing to herpesvirus reactivation
Journal of Allergy and Clinical Immunology · 2022
Single-cell profiling of immune system alterations in lymphoid, barrier and solid tissues in aged mice
Nature Aging · 2021
IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation
Science Immunology · 2021
Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature
Acta Neuropathologica · 2021
Keratinocytes control skin immune homeostasis through de novo-synthesized glucocorticoids.
Science advances · 2021
CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation.
Autophagy · 2020
The CNS Immune Landscape from the Viewpoint of a T Cell
Trends in Neurosciences · 2019
Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation.
Science Immunology · 2019
ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4+ T cell pathogenicity during CNS inflammation.
Proceedings of the National Academy of Sciences of the United States of America · 2017
The immunoproteasome subunit LMP7 is required in the murine thymus for filling up a hole in the T cell repertoire.
European journal of immunology · 2017
No prolongation of skin allograft survival by immunoproteasome inhibition in mice.
Molecular immunology · 2017
Inhibiting the immunoproteasome exacerbates the pathogenesis of systemic Candida albicans infection in mice.
Scientific reports · 2016
Inhibition and deficiency of the immunoproteasome subunit LMP7 attenuates LCMV-induced meningitis.
European journal of immunology · 2015
The Ubiquitin-like Modifier FAT10 Is Selectively Expressed in Medullary Thymic Epithelial Cells and Modifies T Cell Selection.
Journal of immunology (Baltimore, Md. : 1950) · 2015
The immunoproteasome: a novel drug target for autoimmune diseases.
Clinical and experimental rheumatology · 2015
Analgesia in mice with experimental meningitis reduces pain without altering immune parameters.
ALTEX · 2015
Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis.
EMBO molecular medicine · 2014